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This process is believed to contribute to the progression of HIV into AIDS and to the overall pathogenesis of diseases associated with HIV infections [18]

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Here, we provide the first evidence of improved healthspan and age-related survival with a therapeutic mAb by demonstrating that treatment with an IGF-1R antagonist in older mice significantly and preferentially improves several indices of healthspan, reduced death from neoplastic disease, and increased mean and median lifespan in females