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Identifying the specific, dysregulated ROS-generating pathways in individual PCOS patients could pave the way for precision medicine, where therapies are tailored to inhibit the most active or relevant ROS sources in a particular individual

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The ability of benfotiamine to inhibit three major pathways (the hexosamine pathway, the AGE formation pathway, and the diacylglycerol (DAG)-PKC pathway) simultaneously might be clinically useful in preventing the development and progression of diabetic complications