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Therefore, the balance between ROS production and mitochondrial antioxidant defense capacity may determine the degree of ROS-induced oxidative damage and associated mitochondrial dysfunction in the inner ear sensory hair cells or spiral ganglion neurons, which require larger amounts of energy to process sounds

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Several studies reported DMEs could respond to the hepatic steatosis by protecting hepatocytes from free radicals 6,7 , additionally, GSTs are always considered as the scavenger of reactive oxygen species