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Novo Nordisk filed an NDA with the FDA on 18 December 2025 for CagriSema, the fixed-dose cagrilintide/semaglutide combination, but that submission covers the combination product and is still under review — it is not an approval of cagrilintide on its own

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Still, it occurs when there's an excess of copper in the body that can come from multiple sources (diet, supplements, and external exposure)