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[DOI] [PMC free article] [PubMed] [Google Scholar] 203.Hess E.M., Riggs L.M., Michaelides M., Gould T.D

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Our experiments in mouse models of mild hyperhomocysteinemia caused by a deficiency in cystathionine beta-synthase in CBS +/− (heterozygous deficient) mice found that increased plasma total homocysteine caused abnormal responses to endothelium-dependent vasodilators