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Furthermore, Pt-induced ROS production can also promote the secretion of proinflammatory cytokines, for example, TNF-α, interleukin-1β (IL-1β), interleukin-6 (IL-6), chemokine ligand 2 (CCL2), and so on (Ozturk et al., 2005)

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The hippocampal subregions have distinct roles: CA1 is crucial for learning and memory consolidation, CA2 is linked to social memory, and CA3 is vital for pattern separation and memory encoding