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In the group of patients with subclinical hypothyroidism and HT, mean total oxidant status (TOS) and oxidative stress index (OSI) were significantly higher in individuals, who developed overt disorders, which raised the suspicion that oxidative stress may be an effective risk factor in the development of overt hypothyroidism in the course of HT [38]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Vedadghavami A, Wagner EK, Mehta S, He T, Zhang C, Bajpayee AG