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Reactive metabolites from lipid peroxidation disrupt essential cellular structures, initiating cell death and DAMP release—a process further amplified by antioxidant depletion and exemplified in SLE, where neutrophils undergo ferroptosis and NETosis, activating TLR-dependent ROS generation that propagates inflammatory tissue injury (76, 87, 113–115)​

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Regenerative Medicine Reviews , 2021 Follow Sterile Injection Protocols Even if the peptide is clean, poor injection technique can lead to irritation, infection, or subcutaneous tissue damage

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