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Statistical analysis Statistical analysis was performed by parametric one-way analysis of variance, with post-hoc Newman-Keuls test and non-parametric Kruskal-Wallis test and subsequently the Mann-Whitney U test to compare groups

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Standard treatments like surgery, radiotherapy, and chemotherapy often lead to adverse effects such as oral mucositis (OM) and gastrointestinal complications, which negatively impact patients' quality of life (QoL)