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In contrast, high-dose, long-term H 2 O 2 stimulation significantly increases intracellular ROS levels, downregulates mTOR expression, and inhibits cell proliferation
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Size:5000 Β΅g - Cat. No. IK0300-5000
This eventually prevents mitochondrial damage and the cytosolic release of oxidized mtDNA, a direct activator of NLRP3, limiting the processing of mature IL-1Ξ² 69