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For some other types of affinity purifications, like Nickel Beads and His-tags, regeneration means that we actually strip the nickel ion off of the beads and regenerate them by adding new nickel onto the beads

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ESRD Patients on Hemodialysis The recommended starting dose is 10 to 20 mg/kg dry body weight as a slow 2 to 3 minute bolus injection into the venous return line after each dialysis session