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No brain atrophy was evident until animals reached at least until 3 months of age for GCLC floxed X Iba1-Cre (Fig

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The toolbox of cleavable linkers was further expanded by Bargh and coworkers where they utilized 3- O -sulfo-β-galactose linker to be sequentially cleaved by two lysosomal enzymes i.e., arylsulfatase A and β-gal 73

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